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The Ten Most Recent Comments By yw8808

From Talk

Possiblity of contamination of coumarin in cinnamon?

hi i'm a science student who's currently doing a research on coumarin, so i was very interested in your blog :D

well, from the little research i've done so far, coumarin seems to be toxic to rats and that is why it is used as a rodenticide. In rat's organism, it can react to become 3,4-coumarin epoxide, which is highly toxic and causes internal hemorrhage. However, in human's body, thanks to the cytochrome P450 2A6, coumarin is converted to a non toxic substance 7-hydroxycoumarin. In addition, because it causes tumor in rat's liver, there are many rumours saying that it is toxic to human liver as well. I personally think that further research has to be done before stating such a thing.

As for the relationship between cinnamon and coumarin, i think it is not so well based. But on the other hand, it is never good to be addicted to anything, so better lighten your cinnamon intake dosage!

Responses to Comments by yw8808

From Talk

Possiblity of contamination of coumarin in cinnamon?

Thank you for the link on Ceylon Cinnamon. I was amazed how sweet it tastes compared to the Cassia we buy locally.

The Cinnamon was delivered to me within 3 days from Ceylon which is half around the world.

From Talk

Possiblity of contamination of coumarin in cinnamon?

i would be very interested to know what you use three bottles a week in/on. i go through maybe one bottle every year, and i love cinnamon.

From Talk

Possiblity of contamination of coumarin in cinnamon?

You should use Ceylon Cinnamon as the coumarin content is very low.

Please click the below link to identify real cinnamon from Cassia.

http://www.ceylon-cinnamon.com/Identify-Cinnamon.htm

From Talk

Possiblity of contamination of coumarin in cinnamon?

Cinnamon in large doses or for long term use is not recommended.

If you are using cinnamon for glucose control, a less toxic form is Cinnulin PF. One brand is Cinnabetic II.

Notice that the previous article did say that, regarding coumarin, it's "largely metabolized" in humans to a form with lower toxicity.

From Talk

Possiblity of contamination of coumarin in cinnamon?

Yes, there is a connection between cinnamon and coumarin! There are many articles. Here is part of one: 3rd paragraph mentions limiting your intake of cinnamon.

from: http://www.answers.com/topic/coumarin

Coumarin toxicity
Coumarin is often found in tobacco products and artificial vanilla substitutes, though it has been banned as a food additive in numerous countries since the mid-20th century because it is moderately toxic to the liver and kidneys, with an LD50 of 275 mg/kg - low compared to related compounds. Although only somewhat dangerous to humans, coumarin is a potent rodenticide: rats and other rodents largely metabolize it to 3,4-coumarin epoxide, a toxic compound that can cause internal hemorrhage and death. Humans largely metabolize it to 7-hydroxycoumarin, a compound of lower toxicity.

Coumarin was banned as a food additive in the United States in 1978. OSHA considers this compound to be only a lung-specific carcinogen, and "not classifiable as to its carcinogenicity to humans" [1]. Coumarin was banned as an adulterant in cigarettes by tobacco companies in 1997, but due to the lack of reporting requirements to the US Department of Health and Human Services it was still being used as a flavoring additive in pipe tobacco.[citation needed] Coumarin is currently listed by the United States Food and Drug Administration (FDA) among "Substances Generally Prohibited From Direct Addition or Use as Human Food", according to 21 CFR 189.130 [2][3], but some natural additives containing coumarin (such as sweet woodruff) are allowed "in alcoholic beverages only" (21 CFR 172.510 [4]). In Europe, such beverages are very popular, for example Maiwein (white wine with woodruff) and Żubrówka (vodka flavored with bison grass).

European health agencies have warned against consuming high amounts of cassia bark, one of the four species of cinnamon, because of its coumarin content. [1]

Coumarin should be avoided by people with perfume allergy[2].

Compounds
Compounds within the coumarin family include:

warfarin,
brodifacoum,[3][4]
bromadiolone,[5]
coumafuryl,[6] and
difenacoum.[7]
With the exception of warfarin, the remaining compounds are used as rodenticides.