San Francisco dining suggestions

I'm taking a long overdue trip to San Francisco at the end of February and I'm looking for some suggestions. I did Una Pizza Napoletana last trip and might do it again this time, and Abbot's Cellar is also on the list. I wanted to do State Bird and Flour + Water, but it looks like they're already booked up for when I'm in town. Anybody have some can't miss spots? Bonus points for all recommendations with a great beer list.

 

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