East Coast Seafood

I wasn't sure if I should post this here or in Eating Out. I'm not necessarily looking for specific restaurants, but rather regional specialities. Anyway, I'm a midwest girl flying into Boston, and then driving down to Falmouth, right across from Martha's Vineyard. I love love love seafood of all kinds and can't wait to get it straight from the source. Is there something special that I should look for in that area?
I plan on putting a serious hurt on the lobster population.

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