Serious Eats: Talk
HFCS Causes More Weight Gain Than Sugar in Scientific Study
http://www.princeton.edu/main/news/archive/S26/91/22K07/
Obviously one study ain't an ironclad argument...but since it's not THAT hard to avoid HFC...and since sugar tastes better anyway...why mess around with it?
Rats with access to high-fructose corn syrup gained significantly more weight than those with access to table sugar, even when their overall caloric intake was the same.
"When rats are drinking high-fructose corn syrup at levels well below those in soda pop, they're becoming obese -- every single one, across the board. Even when rats are fed a high-fat diet, you don't see this; they don't all gain extra weight."