Marcello's bills itself as serving New York-style slices, and the large, foldable cuts speak to this. But, I didn't spend two years in Brooklyn for nothin'. I know what my California pizzas are great for: the toppings.
'Marcello's Pizza' on Serious Eats
As a general rule, any neighborhood that supports a healthy nightlife seems to support a healthy pizzalife. San Francisco's Castro district is no different—four different slice shops sit within a block of the neighborhood's nexus at Eighteenth Street. Among these, Marcello's Pizza stands out for reputation, as I've had quite a few folks tell me they count it as their favorite slice in the city.